Comparação dos marcadores de alteração na deglutição entre pacientes com e sem Covid-19 pós-intubação orotraqueal / Comparison of swallowing alteration markers between patients with and without Covid-19 post-orotracheal intubation

RESUMO Objetivo comparar os marcadores de alteração na deglutição de pacientes com e sem COVID-19 e estudar as variáveis preditivas de contraindicação da alimentação por via oral em pacientes com necessidade de intubação orotraqueal prolongada. Métodos estudo caso-controle, retrospectivo, com coleta de prontuário de variáveis clínicas e demográficas e da avaliação clínica da deglutição. As variáveis coletadas foram comparadas estatisticamente entre pacientes com COVID-19 (grupo estudo -GE) e sem COVID-19 (grupo-controle - GC). A análise de regressão de robusta de Poisson foi utilizada para avaliar o efeito da COVID-19 e das demais variáveis na contraindicação da alimentação por via oral. Resultados foram incluídos 351 pacientes, 269 no GE e 82 no GC. Pacientes do GE apresentaram menor idade, quando comparados ao GC (50,7 ± 12,8). O tempo total de intubação orotraqueal foi significativamente maior no GE. Os pacientes do GE apresentaram maior prevalência de tosse fraca, disfonia, piores graus de disfagia e maior ocorrência de contraindicação da alimentação por via oral. Na análise bivariada, verificou-se que os pacientes com COVID-19 apresentaram 65% maior probabilidade dessa contraindicação. Entretanto, quando a COVID-19 foi ajustada com outras variáveis clínicas e demográficas, verificou-se que as estas apresentaram maior influência sobre a contraindicação de alimentação por via oral do que a COVID-19. Conclusão a intubação orotraqueal prolongada teve pior efeito nos marcadores de alteração na deglutição e na reintrodução da via oral de pacientes com COVID-19. A idade maior que 60 anos, tempo de intubação orotraqueal maior que cinco dias, reintubação e delirium demonstraram ser preditivas de contraindicação da alimentação por via oral em pacientes intubados.

ABSTRACT Purpose To compare the swallowing alteration markers in patients with and without COVID-19 and to study the predictive variables of oral feeding contraindication in patients requiring prolonged orotracheal intubation. Methods Retrospective case-control study, with medical record data collection of clinical and demographic variables and the clinical evaluation of swallowing. The collected variables were statistically compared between patients with COVID-19 (SG) and without COVID-19 (CG). Robust Poisson regression analysis was used to evaluate the effect of COVID-19 and other variables on oral feeding contraindication. Results 351 patients were included, 269 in the SG and 82 in the CG. Patients in the SG were younger when compared to the CG (50.7 ± 12.8). The total time of orotracheal intubation was significantly longer in the SG. The patients in the SG had a higher prevalence of weak cough, dysphonia, worse degrees of dysphagia and higher occurrence of contraindication of oral feeding. In the bivariate analysis, it was found that patients with COVID-19 were 65% more likely to have oral feeding contraindication. However, when COVID-19 was adjusted with other clinical and demographic variables, it was found that these variables had a greater influence on the contraindication of the oral feeding than the COVID-19. Conclusion Prolonged orotracheal intubation had a worse effect on alteration markers in swallowing and reintroduction of the oral feeding in COVID-19 patients. Age over 60 years, orotracheal intubation time greater than 5 days, reintubation, and delirium were shown to be predictive of oral feeding contraindication in intubated patients.

Postswallow voice modification: compatibility with videofluoroscopy findings. / Modificação da voz após deglutição: compatibilidade com achados da videofluoroscopia.

PURPOSE: Verify whether voice modification after swallowing is associated with videofluoroscopic examination data. METHODS: 27 patients with oropharyngeal dysphagia underwent recording of sustained phonation of vowel /a/ before and after swallowing during videofluoroscopy. The GRBAS scale and the wet voice parameter were used to evaluate the data. Videofluoroscopy results showed stasis of food in the valleculae and piriform recesses, laryngeal penetration, tracheal aspiration, and degree of dysphagia. RESULTS: Decreased dysphonia grade and asthenia and increased strain were observed after swallowing, with no difference for the wet voice parameter. Sensitivity and specificity of ± 50% were observed for food stasis in the valleculae and piriform recesses. Sensitivity values of 80 and 66-75% were observed for detection of laryngeal penetration and tracheal aspiration and modification of vocal strain, respectively. Negative predictive values of 77-91% were found for the three assessment parameters with no correlation with the degree of oropharyngeal dysphagia. CONCLUSION: Modification of the GRBAS scale parameters after swallowing showed good compatibility with videofluoroscopy findings.

OBJETIVO: Verificar se a modificação da voz após a deglutição relaciona-se com os dados do exame de videofluoroscopia. MÉTODO: 27 indivíduos com disfagia orofaríngea realizaram a gravação da vogal sustentada /a/ antes e após a deglutição durante exame de videofluoroscopia. Utilizou-se a escala GRBAS e acrescentou-se o aspecto voz molhada para avaliação dos dados. Em relação ao exame, verificou-se estase de alimento em valéculas e recessos piriformes, penetração laríngea, aspiração traqueal e grau de disfagia. RESULTADOS: Houve diminuição do grau de alteração e astenia e aumento da tensão fonatória após a deglutição, sem diferença para o parâmetro voz molhada. Obteve-se sensibilidade e especificidade de ±50% para estase em recessos piriformes e valéculas; porém, sensibilidade de 80% para detecção de penetração e de 66-75% para aspiração e modificação da tensão fonatória, com 77-91% de valores preditivos negativos para os três parâmetros de avaliação, sem correlação com o grau de disfagia. CONCLUSÃO: A modificação dos parâmetros da escala GRBAS após a deglutição apresentou boa compatibilidade com achados da videofluoroscopia.

Complicações Clínicas da disfagia em pacientes internados em uma UTI / Clinic Complications of dysphagia in patients admitted to an ICU / Las complicaciones clínicas de la disfagia en pacientes ingresados en una UCI

Introdução: As Unidades de Terapia Intensiva (UTI) são locais destinados à atenção e cuidados de pacientes clinicamente comprometidos. A intervenção fonoaudiológica precoce visa identificar rapidamente a disfagia, prevenindo suas complicações clínicas. A avaliação clínica à beira do leito é atualmente a forma mais utilizada. Objetivo: relacionar a presença de disfagia e as complicações clínicas em pacientes adultos com diferentes doenças de base, internados em uma UTI. Métodos: Estudo retrospectivo, descritivo, realizado por análise de protocolos fonoaudiológicos dos pacientes atendidos em uma UTI, entre julho de 2012 e abril de 2014. Esta pesquisa foi aprovada pelos Comitês de Ética em Pesquisa das instituições participantes. Resultados: A amostra contou com 110 pacientes, a maioria encaminhada com quadro clínico de alteração pulmonar e/ou neurológica, com média de idade de 60,3 anos. Encontraram-se associações significativas da disfagia com o diagnóstico de desnutrição (p=0,020) e uma tendência de associação com os pacientes submetidos à traqueostomia (p=0,058). Observou-se que o tempo de ventilação mecânica é quatro dias superior, em mediana, nos pacientes com disfagia, e que a cada dia que um paciente passa em ventilação mecânica aumenta em 10% a chance de apresentar alteração de deglutição. Conclusão: As complicações clínicas encontradas nos pacientes submetidos à avaliação fonoaudiológica com diagnóstico de disfagia foram a desnutrição e a idade, visto que o grau de disfagia varia e se agrava com o avançar da idade. A atuação fonoaudiológica permite o diagnóstico precoce da disfagia, reduzindo o tempo de internação hospitalar e proporcionando melhor qualidade de vida.

Introduction: The Intensive Care Units (ICUs) are premises for the attention and care of medically compromised patients. Early speech-language therapy aims to quickly identify dysphagia, preventing clinical complications. Clinical evaluation at the bedside is a currently used form to identify. Objective: To relate the presence of dysphagia and clinical complications in adult patients with different underlying diseases hospitalized in an ICU. Methods: A retrospective, descriptive study conducted by analysis of speech-language therapy protocols of patients admitted to an ICU from July 2012 to April 2014. This study was approved by the Ethics Committee in Research of the participating institutions. Results: The sample included 110 patients, most sent with clinical pulmonary and / or neurological disorder, with mean age of 60.3 years. They found significant associations of dysphagia diagnosed with malnutrition (p = 0.020) and a trend of association with patients undergoing tracheostomy (p = 0.058). It was observed that the mechanical ventilation is superior four days, on average, in patients with dysphagia and that every day that a patient goes on mechanical ventilation increases by 10% the chance to present swallowing change. Conclusion: The clinical complications found in patients undergoing clinical assessment with dysphagia were malnutrition and age, whose dysphagia level varies and worsens with age. The speech therapy allows early diagnosis of dysphagia, reducing the length of hospital stay and providing better quality of life to the patient.

Introducción: Unidades de cuidados intensivos (UCI) son premisas para la atención y cuidado de los pacientes médicamente comprometidos. Terapia del habla temprana tiene como objetivo identificar rápidamente la disfagia, la prevención de complicaciones clínicas. La evaluación clínica a pie de cama es actualmente la forma más ampliamente utilizada. Objetivo: relacionar la presencia de disfagia y complicaciones clínicas en pacientes adultos hospitalizados en una UCI. Metodos: Estudio retrospectivo, descriptivo llevado a cabo mediante el análisis de protocolos de terapia del habla de los pacientes ingresados en una UCI de julio de 2012 hasta abril de 2014. Este estudio fue aprobado por el Comité de Ética en Investigación de las instituciones participantes. Resultados: La muestra incluyó a 110 pacientes, la mayoría enviados con clínica pulmonar y / o trastorno neurológico, con edad media de 60,3 años. Ellos encontraron asociaciones significativas de disfagia diagnosticados con desnutrición (p = 0,020) y una tendencia a la asociación con los pacientes sometidos a traqueotomía (p = 0,058). Se observó que la ventilación mecánica es superior a cuatro días, en promedio, en los pacientes con disfagia y que cada día que un paciente va en aumento de la ventilación mecánica en un 10% la posibilidad de presentar tragar cambio. Conclusión: Las complicaciones clínicas encontradas en pacientes con el diagnóstico disfagia eran la desnutrición y la edad. La terapia del habla permite el diagnóstico precoz de la disfagia, la reducción de la duración de la estancia hospitalaria y ofrece una mejor calidad de vida.

Chest CT findings in patients with dysphagia and aspiration: a systematic review.

The objective of this systematic review was to characterize chest CT findings in patients with dysphagia and pulmonary aspiration, identifying the characteristics and the methods used. The studies were selected from among those indexed in the Brazilian Virtual Library of Health, LILACS, Indice Bibliográfico Español de Ciencias de la Salud, Medline, Cochrane Library, SciELO, and PubMed databases. The search was carried out between June and July of 2016. Five articles were included and reviewed, all of them carried out in the last five years, published in English, and coming from different countries. The sample size in the selected studies ranged from 43 to 56 patients, with a predominance of adult and elderly subjects. The tomographic findings in patients with dysphagia-related aspiration were varied, including bronchiectasis, bronchial wall thickening, pulmonary nodules, consolidations, pleural effusion, ground-glass attenuation, atelectasis, septal thickening, fibrosis, and air trapping. Evidence suggests that chest CT findings in patients with aspiration are diverse. In this review, it was not possible to establish a consensus that could characterize a pattern of pulmonary aspiration in patients with dysphagia, further studies of the topic being needed.

Chest CT findings in patients with dysphagia and aspiration: a systematic review / Achados de TC de tórax em pacientes com disfagia e aspiração pulmonar: uma revisão sistemática

ABSTRACT The objective of this systematic review was to characterize chest CT findings in patients with dysphagia and pulmonary aspiration, identifying the characteristics and the methods used. The studies were selected from among those indexed in the Brazilian Virtual Library of Health, LILACS, Indice Bibliográfico Español de Ciencias de la Salud, Medline, Cochrane Library, SciELO, and PubMed databases. The search was carried out between June and July of 2016. Five articles were included and reviewed, all of them carried out in the last five years, published in English, and coming from different countries. The sample size in the selected studies ranged from 43 to 56 patients, with a predominance of adult and elderly subjects. The tomographic findings in patients with dysphagia-related aspiration were varied, including bronchiectasis, bronchial wall thickening, pulmonary nodules, consolidations, pleural effusion, ground-glass attenuation, atelectasis, septal thickening, fibrosis, and air trapping. Evidence suggests that chest CT findings in patients with aspiration are diverse. In this review, it was not possible to establish a consensus that could characterize a pattern of pulmonary aspiration in patients with dysphagia, further studies of the topic being needed.

RESUMO O objetivo deste estudo foi realizar uma revisão sistemática dos achados de TC de tórax que caracterizem aspiração pulmonar em pacientes com disfagia, identificando as características e os métodos utilizados. Para a seleção dos estudos, foram utilizadas as bases de dados da Biblioteca Virtual em Saúde, LILACS, Indice Bibliográfico Español de Ciencias de la Salud, Medline, Biblioteca Cochrane, SciELO e PubMed. A busca foi realizada no período entre junho e julho de 2016. Foram incluídos e revisados cinco artigos, todos realizados nos últimos cinco anos, publicados em língua inglesa e oriundos de diferentes países. O tamanho da amostra nos estudos selecionados variou de 43 a 56 pacientes, com predominância de sujeitos adultos e idosos. Os achados tomográficos em pacientes com aspiração relacionada à disfagia foram variados, abrangendo bronquiectasias, espessamento da parede brônquica, nódulos pulmonares, consolidações, derrame pleural, atenuação em vidro fosco, atelectasias, espessamento septal, fibrose, aprisionamento aéreo, entre outros. As evidências sugerem que os achados de TC de tórax em pacientes que apresentam aspiração são diversificados. Nesta revisão, não foi possível estabelecer um consenso que pudesse caracterizar um padrão de aspiração pulmonar nos pacientes com disfagia, sendo importantes investigações futuras sobre o assunto.

Association between functionality assessment scales and the severity of dysphagia post-stroke. / Associação entre escalas de avaliação de funcionalidade e severidade da disfagia pós-acidente vascular cerebral.

PURPOSE: The aim of this study was to investigate the association between the results of functionality scales and dysphagia severity determined from videofluoroscopy swallowing study (VSS) in post-stroke patients. METHODS: A retrospective study of 109 VSS analysis of post-stroke patients. From the exams was collected information on the diagnosis of dysphagia severity and evaluated regarding the swallowing functionality in an independent way by two evaluators. RESULTS: A high number of discrete dysphagia was observed. In one third of dysphagic patients it was noticed the presence of tracheal aspiration. There was a significant association between the scores of Functional Oral Intake Scale and Dysphagia Outcome and Severity Scale in post-stroke patients which means when the swallowing is highly compromised, the level of intake by mouth will be smaller according to the evaluators' analysis (p < 0.001). CONCLUSION: There is an association between the scales and it can be used as evaluative benchmarks and in the management of clinical Speech Pathology intervention.

Modificação da voz após deglutição: compatibilidade com achados da videofluoroscopia / Postswallow voice modification: compatibility with videofluoroscopy findings

RESUMO Objetivo Verificar se a modificação da voz após a deglutição relaciona-se com os dados do exame de videofluoroscopia. Método 27 indivíduos com disfagia orofaríngea realizaram a gravação da vogal sustentada /a/ antes e após a deglutição durante exame de videofluoroscopia. Utilizou-se a escala GRBAS e acrescentou-se o aspecto voz molhada para avaliação dos dados. Em relação ao exame, verificou-se estase de alimento em valéculas e recessos piriformes, penetração laríngea, aspiração traqueal e grau de disfagia. Resultados Houve diminuição do grau de alteração e astenia e aumento da tensão fonatória após a deglutição, sem diferença para o parâmetro voz molhada. Obteve-se sensibilidade e especificidade de ±50% para estase em recessos piriformes e valéculas; porém, sensibilidade de 80% para detecção de penetração e de 66-75% para aspiração e modificação da tensão fonatória, com 77-91% de valores preditivos negativos para os três parâmetros de avaliação, sem correlação com o grau de disfagia. Conclusão A modificação dos parâmetros da escala GRBAS após a deglutição apresentou boa compatibilidade com achados da videofluoroscopia.

ABSTRACT Purpose Verify whether voice modification after swallowing is associated with videofluoroscopic examination data. Methods 27 patients with oropharyngeal dysphagia underwent recording of sustained phonation of vowel /a/ before and after swallowing during videofluoroscopy. The GRBAS scale and the wet voice parameter were used to evaluate the data. Videofluoroscopy results showed stasis of food in the valleculae and piriform recesses, laryngeal penetration, tracheal aspiration, and degree of dysphagia. Results Decreased dysphonia grade and asthenia and increased strain were observed after swallowing, with no difference for the wet voice parameter. Sensitivity and specificity of ± 50% were observed for food stasis in the valleculae and piriform recesses. Sensitivity values of 80 and 66-75% were observed for detection of laryngeal penetration and tracheal aspiration and modification of vocal strain, respectively. Negative predictive values of 77-91% were found for the three assessment parameters with no correlation with the degree of oropharyngeal dysphagia. Conclusion Modification of the GRBAS scale parameters after swallowing showed good compatibility with videofluoroscopy findings.

Associação entre escalas de avaliação de funcionalidade e severidade da disfagia pós-acidente vascular cerebral / Association between functionality assessment scales and the severity of dysphagia post-stroke

RESUMO Objetivo O objetivo deste estudo foi verificar a associação entre os resultados das escalas de funcionalidade e severidade da disfagia determinadas a partir de exames de videofluoroscopia em pacientes pós-AVC. Método Estudo observacional, retrospectivo e descritivo, com análise de 109 exames de Videofluoroscopia da Deglutição de pacientes pós-AVC. Dos exames da amostra foram coletadas informações quanto ao diagnóstico da severidade da disfagia e avaliados quanto à funcionalidade da deglutição de maneira independente por dois avaliadores. Resultados Foi constatada uma alta prevalência de disfagia classificada como discreta. Nos pacientes com disfagia foi observada a presença de aspiração laringotraqueal em um terço da amostra. Verificou-se associação significativa entre os escores das escalas Functional Oral Intake Scale e Dysphagia Outcome and Severity Scale em pacientes pós-AVC, ou seja, quanto maior o comprometimento da deglutição, menor o nível de ingestão por via oral na análise dos avaliadores (p < 0,001). Conclusão Há associação entre as escalas, podendo elas serem utilizadas como balizadores avaliativos e no gerenciamento da intervenção clínica fonoaudiológica.

ABSTRACT Purpose The aim of this study was to investigate the association between the results of functionality scales and dysphagia severity determined from videofluoroscopy swallowing study (VSS) in post-stroke patients. Methods A retrospective study of 109 VSS analysis of post-stroke patients. From the exams was collected information on the diagnosis of dysphagia severity and evaluated regarding the swallowing functionality in an independent way by two evaluators. Results A high number of discrete dysphagia was observed. In one third of dysphagic patients it was noticed the presence of tracheal aspiration. There was a significant association between the scores of Functional Oral Intake Scale and Dysphagia Outcome and Severity Scale in post-stroke patients which means when the swallowing is highly compromised, the level of intake by mouth will be smaller according to the evaluators’ analysis (p < 0.001). Conclusion There is an association between the scales and it can be used as evaluative benchmarks and in the management of clinical Speech Pathology intervention.

Pulmonary computed tomography findings in patients with chronic aspiration detected by videofluoroscopic swallowing study.

OBJECTIVE: To demonstrate CT findings in patients with chronic aspiration compared with a control group without aspiration, as detected by the videofluoroscopic swallowing study (VFSS). METHODS: This retrospective, observational study included patients with and without diagnoses of aspiration confirmed by VFSS, who underwent CT examination of the lungs between 2010 and 2014. Two radiologists blinded to the presence of aspiration reviewed the images to detect the presence of any abnormality. Consensus was reached with a third radiologist. CT pulmonary findings (bronchial thickening, bronchiolectasis, centrilobular nodules, ground-glass opacities, atelectasis, consolidation and air trapping) were compared between the groups using the χ(2) test, with a significance level of 0.05. RESULTS: A total of 56 patients (28 patients with diagnoses of aspiration; 52% male, mean age 65 ± 15 years) were included in the study. Patients with aspiration were more likely to than those in the control group to demonstrate atelectasis, centrilobular nodules, bronchiolectasis, consolidation and ground-glass opacities (all p < 0.05), with a significant predilection for the lower lobes (p < 0.001). Bronchial wall thickening and air trapping did not differ between groups. CONCLUSION: Atelectasis, centrilobular nodules, bronchiolectasis, consolidation and ground-glass opacities occurred more frequently in patients with aspiration than in those without aspiration, with a pronounced tendency for distribution in the lower lobes. ADVANCES IN KNOWLEDGE: CT findings of aspiration are very important, as pulmonary symptoms may be the first manifestation of this disorder. Knowledge of these findings is essential to enable the early diagnosis of aspiration disorders and prevent lung damage.

Computed tomographic pulmonary changes in patients with chronic rhinosinusitis.

OBJECTIVE: To investigate whether patients with a diagnosis of chronic rhinosinusitis (CRS) show characteristic pulmonary changes on chest CT compared with a control group without sinusopathy. METHODS: This retrospective, observational study included patients with and without a diagnosis of CRS who underwent CT examination of the lungs between 2012 and 2014. Two radiologists, who were blinded for the presence of CRS, reviewed the scans for the presence of any abnormalities consensually. The χ(2) test was used for correlative analysis, with a significance level of 0.05. RESULTS: A total of 123 CT series (51.2% from male patients, mean age 41 ± 16 years) were reviewed, including those from 59 (48%) patients with a diagnosis of CRS. Patients with CRS were more likely than the control group to exhibit atelectasis, bronchiolectasis, centrilobular nodules and ground-glass opacities (all p < 0.05), with a significant predilection for middle lobe and lingular involvement observed (p < 0.001). Other abnormalities, such as bronchial wall thickening and air trapping, did not differ between groups. CONCLUSION: Atelectatic changes, ground-glass opacities, bronchiolectasis and centrilobular nodules are the most frequent abnormalities associated with CRS, with peculiar middle lobe and lingular involvement observed on chest CT examinations. ADVANCES IN KNOWLEDGE: CRS is a frequent disorder that displays typical pulmonary changes at CT. The recognition of such findings can prevent patients with this condition from undergoing unnecessary investigations that might be based on the presence of the aforementioned radiological features.

Vocal Variability Post Swallowing in Individuals with and without Oropharyngeal Dysphagia.

Introduction Voice modification after swallowing may indicate changes in the transit of the bolus. Objective The aim of this study is to verify the use of perceptual voice analysis to detect oropharyngeal dysphagia. Study Design Case series. Methods Twenty-seven patients with dysphagia as diagnosed by videofluoroscopy and 25 without were evaluated. The sustained vowel /a/ was recorded before this exam and after swallowing different consistencies (pasty, liquid and solid). For the voice evaluation, the GRBAS scale (grade, roughness, breathiness, asthenia and strain) and the parameter "wet voice" were used. Three judges blinded to study group and time of emission performed voice analysis. Results Individuals with dysphagia showed significant decrease in grade of voice and asthenia and increase in strain after swallowing pasty substances, differing from individuals without dysphagia who showed no modification of the parameters after swallowing. The wet voice parameter showed no difference after swallowing in both study groups. Conclusion The decrease in grade and asthenia and increased strain are indicative of a swallowing disorder, indicating increased vocal strain to clean the vocal tract of food. The modification of vocal production after swallowing proved to be a trusted resource for detection of swallowing disorders.

Vocal Variability Post Swallowing in Individuals with and without Oropharyngeal Dysphagia

Introduction Voice modification after swallowing may indicate changes in the transit of the bolus. Objective The aim of this study is to verify the use of perceptual voice analysis to detect oropharyngeal dysphagia. Study Design Case series. Methods Twenty-seven patients with dysphagia as diagnosed by videofluoroscopy and 25 without were evaluated. The sustained vowel /a/ was recorded before this exam and after swallowing different consistencies (pasty, liquid and solid). For the voice evaluation, the GRBAS scale (grade, roughness, breathiness, asthenia and strain) and the parameter "wet voice" were used. Three judges blinded to study group and time of emission performed voice analysis. Results Individuals with dysphagia showed significant decrease in grade of voice and asthenia and increase in strain after swallowing pasty substances, differing from individuals without dysphagia who showed no modification of the parameters after swallowing. The wet voice parameter showed no difference after swallowing in both study groups. Conclusion The decrease in grade and asthenia and increased strain are indicative of a swallowing disorder, indicating increased vocal strain to clean the vocal tract of food. The modification of vocal production after swallowing proved to be a trusted resource for detection of swallowing disorders. .

Clinical Scales Predict Significant Videofluoroscopic Dysphagia in Machado Joseph Disease Patients.

BACKGROUND: Although aspiration is one of the main causes of death in SCA, such as SCA3/Machado Joseph disease (SCA3/MJD), clinical studies on dysphagia are lacking for these diseases. The aims of this study were to characterize dysphagia in SCA3/MJD through videofluoroscopy (VF) of swallowing, correlate VF with disease severity criteria and weight loss, and determine the clinical criteria cutoffs for performing VF in the clinical routine, in order to detect aspiration. METHODS: A cross-sectional study on 34 SCA3/MJD patients was performed. Clinical and molecular data, as well as body mass index (BMI), were obtained. Neurological scales, such as the Scale for the Assessment and Rating of Ataxia (SARA), and the Swallowing Quality of Life (SWAL-QOL) questionnaire were applied. The VF scores, Dysphagia Outcome and Severity Scale (DOSS) and penetration/aspiration scale (PAS), were obtained: Moderate-to-severe scores were grouped as "significant dysphagia." RESULTS: Overall, 31 of 34 individuals showed abnormal scores at VF. SARA, BMI, and the domain "eating duration" of SWAL-QOL correlated with VF: Their relation to significant dysphagia (DOSS <4 points or PAS >3) was evaluated through receiver operating characteristic curves. A sensitivity of 100% was equivalent to a cutoff of 15 points on SARA score, 23.72 kg/m2 on BMI, and 60% on eating duration-SWAL-QOL (P < 0.05). CONCLUSION: Significant dysphagia was not related to age at onset, disease duration, or CAG repeat expansion, but with SARA scores, lower BMI, and the domain eating duration of SWAL-QOL. As a guideline for preventing aspiration, we suggest that SARA scores greater than 15 or eating duration-SWAL-QOL lower than 60% should urge VF studies in SCA3/MJD.

Screening tools for dysphagia: a systematic review.

PURPOSE: To perform a systematic review of screening instruments for dysphagia available in the literature. METHODS: For the selection of studies, the following descriptors were used: "questionários", "questionnaires", "transtornos de deglutição", "deglutition disorders", "programas de rastreamento", and "mass screening". The online databases used for the research were Virtual Health Library (LILACS, IBECS, MEDLINE, Cochrane Library, SciELO) and PubMed. The research was performed from April to June 2013. Selection criteria articles in English, Portuguese, and Spanish, regardless of the year of publication, whose title, abstract, or text had any relation to the purpose of the research. After reading the articles in their entirety, identification data and method of the articles were extracted for later analysis. RESULTS: The research carried out from the proposed descriptors produced 1,012 articles. After reviewing the titles, summaries, and fully reading the articles, 20 studies were chosen. The publications on instruments for the identification of dysphagic patients started in 1999, and 50% of the analyzed studies were carried out in the USA. The methods used on the instruments were questionnaires, observation of patient's clinical signals and symptoms, the request for execution of some orofacial movements, and swallowing test with water or food. CONCLUSION: Screening instruments in dysphagia are fairly heterogeneous and have been developed for different audiences with the main objective of identifying patients with swallowing disorders.

Videofluoroscopic swallowing study: esophageal alterations in patients with dysphagia.

CONTEXT: Videofluoroscopic swallowing study is a dynamic exam and allows the evaluation of the complete swallowing process. However, most published studies have only reported alterations in the oropharynx and pharyngoesophageal transition, leaving the analysis of the esophagus as a secondary goal. OBJECTIVES: The goal of this study was to investigate the prevalence of alterations in the esophageal phase thorough videofluoroscopic swallowing study in patients with dysphagia. METHODS: Consecutive patients with dysphagia who underwent videofluoroscopic swallowing study including esophageal analysis between May 2010 and May 2012 had their exams retrospectively reviewed. Patients were classified into two groups: Group I - without a pre-established etiological diagnosis and Group II - with neurological disease. During the exam, the patients ingested three different consistencies of food (liquid, pasty and solid) contrasted with barium sulfate and 19 items were analyzed according to a protocol. The esophageal phase was considered abnormal when one of the evaluated items was compromised. RESULTS: Three hundred and thirty-three (n = 333) consecutive patients were studied - 213 (64%) in Group I and 120 (36%) in Group II. Esophageal alterations were found in 104 (31%) patients, with a higher prevalence in Group I (36.2%), especially on the items esophageal clearance (16.9%) and tertiary contractions (16.4%). It was observed that 12% of individuals in Group I only presented alterations on the esophageal phase. CONCLUSION: Evaluation of the esophageal phase of swallowing during videofluoroscopic swallowing study detects abnormalities in patients with cervical dysphagia, especially in the group without pre-established etiological diagnosis.

Screening tools for dysphagia: a systematic review / Instrumentos de rastreio em disfagia: uma revisão sistemática

Purpose: To perform a systematic review of screening instruments for dysphagia available in the literature. Methods: For the selection of studies, the following descriptors were used: "questionários", "questionnaires", "transtornos de deglutição", "deglutition disorders", "programas de rastreamento", and "mass screening". The online databases used for the research were Virtual Health Library (LILACS, IBECS, MEDLINE, Cochrane Library, SciELO) and PubMed. The research was performed from April to June 2013. Selection criteria articles in English, Portuguese, and Spanish, regardless of the year of publication, whose title, abstract, or text had any relation to the purpose of the research. After reading the articles in their entirety, identification data and method of the articles were extracted for later analysis. Results: The research carried out from the proposed descriptors produced 1,012 articles. After reviewing the titles, summaries, and fully reading the articles, 20 studies were chosen. The publications on instruments for the identification of dysphagic patients started in 1999, and 50% of the analyzed studies were carried out in the USA. The methods used on the instruments were questionnaires, observation of patient's clinical signals and symptoms, the request for execution of some orofacial movements, and swallowing test with water or food. Conclusion: Screening instruments in dysphagia are fairly heterogeneous and have been developed for different audiences with the main objective of identifying patients with swallowing disorders.

Objetivo: Realizar a revisão sistemática dos instrumentos de rastreio em disfagia disponíveis na literatura. Estratégia de pesquisa: Para a seleção dos estudos, foram utilizados os seguintes descritores: "questionários", "questionnaires", "transtornos de deglutição", "deglutition disorders", "programas de rastreamento" e "mass screening" e foram utilizadas as bases de dados: Biblioteca Virtual em Saúde (LILACS, IBECS, MEDLINE, Biblioteca Cochrane, SciELO) e PubMed. A busca foi realizada no período entre abril e junho de 2013. Critérios de seleção: Foram selecionados artigos em Inglês, Português e Espanhol, independentemente do ano de publicação, que possuíam no título, resumo ou corpo do artigo relação com o objetivo da pesquisa. Análise dos dados: Após a leitura dos artigos na íntegra, foram extraídos dados de identificação e métodos dos artigos para posterior análise. Resultados: A pesquisa realizada a partir dos descritores propostos, nas bases de dados utilizadas, gerou o total de 1.012 artigos. Após a análise dos títulos, resumos e leitura dos artigos na íntegra, foram selecionados 20 estudos. As publicações sobre instrumentos para identificação de pacientes disfágicos iniciaram em 1999 e 50% dos artigos analisados foram desenvolvidos nos Estados Unidos. Os métodos empregados nos instrumentos foram: questionários, a observação de sinais e sintomas clínicos do paciente, a solicitação da execução de alguns movimentos orofaciais, teste de deglutição com água ou alimentos. Conclusão: Os instrumentos de rastreio em disfagia são bastante heterogêneos e foram desenvolvidos para diferentes públicos com o objetivo principal de identificar os pacientes com distúrbios de deglutição.

VIDEOFLUOROSCOPIC SWALLOWING STUDY: esophageal alterations in patients with dysphagia / Videofluoroscopia da deglutição: alterações esofágicas em pacientes com disfagia

Context Videofluoroscopic swallowing study is a dynamic exam and allows the evaluation of the complete swallowing process. However, most published studies have only reported alterations in the oropharynx and pharyngoesophageal transition, leaving the analysis of the esophagus as a secondary goal. Objectives The goal of this study was to investigate the prevalence of alterations in the esophageal phase thorough videofluoroscopic swallowing study in patients with dysphagia. Methods Consecutive patients with dysphagia who underwent videofluoroscopic swallowing study including esophageal analysis between May 2010 and May 2012 had their exams retrospectively reviewed. Patients were classified into two groups: Group I - without a pre-established etiological diagnosis and Group II - with neurological disease. During the exam, the patients ingested three different consistencies of food (liquid, pasty and solid) contrasted with barium sulfate and 19 items were analyzed according to a protocol. The esophageal phase was considered abnormal when one of the evaluated items was compromised. Results Three hundred and thirty-three (n = 333) consecutive patients were studied - 213 (64%) in Group I and 120 (36%) in Group II. Esophageal alterations were found in 104 (31%) patients, with a higher prevalence in Group I (36.2%), especially on the items esophageal clearance (16.9%) and tertiary contractions (16.4%). It was observed that 12% of individuals in Group I only presented alterations on the esophageal phase. Conclusion Evaluation of the esophageal phase of swallowing during videofluoroscopic swallowing study detects abnormalities in patients with cervical dysphagia, especially in the group without pre-established etiological diagnosis. .

Contexto A videofluoroscopia da deglutição é um exame dinâmico e permite a avaliação de todo o processo da deglutição, entretanto, a maioria dos estudos publicados relata apenas alterações na orofaringe e transição faringoesofágica, não considerando como importante as alterações esofágicas. Objetivos O objetivo da presente pesquisa foi verificar a prevalência de alterações na fase esofágica à videofluoroscopia da deglutição em pacientes com disfagia. Métodos Pacientes com queixa de disfagia submetidos à videofluoroscopia da deglutição incluindo estudo esofágico entre maio de 2010 e maio de 2012 tiveram seus exames revisados retrospectivamente. Os pacientes foram classificados em dois grupos: Grupo I - sem diagnóstico etiológico pré-estabelecido e Grupo II - com diagnóstico de doença neurológica. Durante o exame os pacientes ingeriram três consistências de alimento (líquido, pastoso e sólido) contrastadas com sulfato de bário e 19 itens foram analisados segundo protocolo. A fase esofágica foi considerada alterada quando um dos itens avaliados estivesse comprometido. Resultados Trezentos e trinta e três (n = 333) pacientes consecutivos foram estudados com 213 (64%) no Grupo I e 120 (36%) no Grupo II. Alterações esofágicas foram identificadas em 104 (31%) pacientes, sendo a prevalência maior no Grupo I (36,2%), principalmente, nos itens clareamento esofágico (16,9%) e contrações terciárias (16,4%). Pudemos observar que 12% dos indivíduos do Grupo I apresentaram somente alteração em fase esofágica. Conclusão Avaliação da fase esofágica durante a videofluoroscopia da deglutição identificou alterações esofágicas em 1/3 dos ...

Association between sleep bruxism and gastroesophageal reflux disease.

STATEMENT OF PROBLEM: Rhythmic masticatory muscle activity, including sleep bruxism (SB), can be induced in healthy individuals by experimental esophageal acidification, which plays an important role in the pathogenesis of gastroesophageal reflux disease (GERD). However, no robust evidence supports the association between SB and GERD. PURPOSE: The purpose of this study was to investigate the association between SB and GERD. MATERIAL AND METHODS: Forty-five individuals were eligible to participate in this observational transversal study at the Gastroenterology Service of the Clinical Hospital of Porto Alegre, Brazil. The participants were classified into 2 groups, those with and without GERD, according to the Montreal Criteria and pH-metry/endoscopy findings. The diagnosis of SB was not assessed in a sleep laboratory but was based on self-report plus clinical inspection, according to the minimal diagnostic criteria of the American Academy of Sleep Medicine. The Lipp Stress Symptom Inventory was used to evaluate self-perceived stress. Univariate and multiple logistic regression analyses were performed with SB as dependent variable and GERD, sex, age, body mass index, and stress as predictors (α=.05; 90% power). RESULTS: The study population included individuals with SB without GERD (13.3%) and individuals with SB with GERD (31.1%). In participants with GERD, the prevalence of SB was 73.7%. Only the variable GERD was significantly associated with SB (P=.017; odds ratio 6.58; 95% confidence interval 1.40-30.98), although adjusted for stress and age. CONCLUSIONS: Sleep bruxism is prevalent in GERD patients, and GERD is highly associated with SB.

Bilateral Killian-Jamieson diverticula demonstrated by videofluoroscopic swallowing study: case report / Divertículo de Killian-Jamieson bilateral demonstrado pela videofluoroscopia da deglutição: relato de caso

The authors report the case of a 56-year-old male patient complaining of dysphagia for solids and food impaction, submitted to videofluoroscopic swallowing study that demonstrated the presence of two esophageal diverticula. The videofluoroscopic swallowing study was critical in the identification and diagnosis of the diverticula, an esophageal cause of dysphagia.

Os autores relatam um caso de paciente do sexo masculino, de 56 anos de idade, com queixa de disfagia para sólidos e impactação de alimentos, submetido a videofluoroscopia da deglutição que demonstrou a presença de dois divertículos esofágicos. O estudo da deglutição foi um importante exame para identificar e diagnosticar o divertículo, uma causa esofágica da disfagia.

Early conditions in the breastfeeding of premature newborn infants.

PURPOSE: To describe the breastfeeding initial conditions for premature infants. METHODS: The sample consisted on 26 mother/baby dyads. The babies had an average of 36.1 weeks corrected gestational age and were hospitalized in a Neonatal Intensive Care Unit in Southern Brazil. Data was collected from medical records, and the observation of the dyads was conducted during feeding, using the Observation and Evaluation of the Breastfeeding Protocol. Favorable and unfavorable behaviors were registered regarding position, responses, suction, affection and anatomy of the breast. After the observation, a questionnaire was applied to the mothers. RESULTS: The best results refer to the position of mother/child and affection and the poorer ones to the infant responses. Statistically significant correlations by the Spearman Correlations Coefficient were observed between some items of the protocol and other study variables. CONCLUSION: Most premature infants from this sample presented a satisfactory initiation on analyzed aspects referring to breastfeeding. Still, we emphasize the need of practices for breastfeeding effectiveness and its encouragement in this population.